I know that the assumptions of multiple imputation require that only the variables are imputed that will be used in the analysis. This webpage is hosted by uclas institute for digital research and education. Despite the widespread use of multiple imputation, there are few guidelines available for checking imputation models. In order to use these commands the dataset in memory must be declared or mi set as mi dataset. Assume a joint multivariate normal distribution of all variables. Iscb news, july 2016 the opening chapters of this book will be useful to the newcomer to missing data, including the nonstatistician. But it is safe to surmise that in most cases a chained equation imputation will be required. More important, multiple imputation was not designed for descriptive statistics. Here, analysis of multiply imputed data is achieved by commands that start with mi. Multiple imputation in a nutshell the analysis factor.
Mi is a statistical method for analyzing incomplete data. Directly maximize the parameter estimate using the observed cases and maximum likelihood method. For data analysis, this command often is a composite prefix mi which is followed by a standard stata command. For epidemiological and prognostic factors studies in medicine, multiple imputation is becoming the standard route to estimating models with missing covariate data under a missingatrandom assumption. Before version 11, analysis of such data was possible with the help of ados.
However, the sampling variance of the multiple imputation estimates was considerably smaller. Just lower the number of iterations between data sets. This particular page is the first of a two part series on implementing multiple imputation techniques in stata. Mi is a sophisticated but flexible approach for handling missing data and is broadly applicable within a range of standard statistical software packages such as r, sas and stata. In this paper, we provide an overview of currently. Multipleimputation reference manual, release 16 stata bookstore. When substituting for a data point, it is known as unit imputation. This book will be helpful to researchers looking for guidance on the use of multiple imputation to address missing data problems, along with examples of correct analysis techniques. Stata has methodmlmv which is full information but relies on multivariate normality. Missing data in stata centre for multilevel modelling, 20 1 introduction to the youth cohort study dataset you will be analysing data from the youth cohort study of england and wales ycs1. I have a problem after multiple imputation in spss, maybe you can help me. Complex tests with multiply imputed data require special commands.
Do i run the sem models on each dataset individually and then manually calculate the pooled estimates. So how do i let stata know that i am working with an imputed dataset. Stata bookstore multipleimputation reference manual. Handling missing values in longitudinal panel data with. The idea of multiple imputation for missing data was first proposed by rubin 1977. What is important is the choice of the proper imputation model, which involves a number of considerations that cannot be mapped out here. Mi proceeds with replicating the incomplete dataset multiple times and replacing the missing data in each replicate with plausible values drawn from an imputation model. The imputations and the analysis were performed using the miice suite in stata with 100 imputations.
This book will be helpful to researchers looking for guidance on the use of multiple imputation to address missing data problems, along with. The following is the procedure for conducting the multiple imputation for missing data that was created by rubin in 1987. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missingdata problem. Most other software packages provide similar possibilities.
Mi is becoming an increasingly popular method for sensitivity analyses in order to assess the impact of missing data. We impute more than one value to get the standard errors right, thus multiple imputation is designed for inference. This series is intended to be a practical guide to the technique and its implementation in stata, based on the questions sscc members are asking the ssccs statistical computing consultants. Royston and white 2011 illustrate this fullyintegrated module in stata using real data from an observational study in ovarian cancer. It should be used within a multiple imputation sequence since missing values are imputed stochastically rather than deterministically. Multipleimputation reference manual statacorp 2009 for details. With this multiple imputated data i want to do a logistic multiple regression to create a clinical prediction model. Why you probably need more imputations than you think. Each data set will have slightly different values for the imputed data because of the.
Statas provides a full suite of multipleimputation methods for the analysis of incomplete data, data for which some values are missing. Flexible imputation of missing data is supported by many examples using real data taken from the authors vast experience of collaborative research, and presents a practical guide for handling missing data under the framework of multiple imputation. Create m sets of imputations for the missing values using an imputation process with a random component. The multiple imputation process contains three phases. However, instead of filling in a single value, the distribution of the observed data is used to estimate multiple values that reflect the uncertainty around the true value. Multiple imputation and its application is aimed at quantitative researchers and students in the medical and social sciences with the aim of clarifying the issues raised by the analysis of incomplete data data, outlining the rationale for mi and describing how to consider and address the issues that arise in its application. We used multiple imputation with statas ice command to handle missing data on all missing variables, following the what works clearinghouse version 4. In mi the distribution of observed data is used to estimate a set of plausible values. Descriptive statistics after multiple imputation statalist. Paul allison, one of my favorite authors of statistical information for researchers, did a study that showed that the most. However, what if you dont have yet the variables you will use in the analysis, but only the source variables you will derive. Multiple imputation has become very popular as a generalpurpose method for handling missing data. A statistical programming story chris smith, cytel inc. The validity of multipleimputationbased analyses relies on the use of an appropriate model to impute the missing values.
May 28, 2014 as far as i know, the mi estimates command is not going to work with the sem builder. This web page contains the log file from the example imputation discussed in the imputing section, plus the graphics it creates. Note that the number of postestimation commands after mi estimation is quite restricted compared to the vast array that is usually offered by stata. In the imputation model, the variables that are related to missingness, can be included. Jan 16, 2015 missing data is a ubiquitous problem in studies using patientreported measures, decreasing sample sizes and causing possible bias. Mplus has a full information estimator which is also robust to nonnormality. Proceeding to a little more detail, we discuss imputation models available in ice for di erent types of variables with. A variety of imputation approaches whenever a single imputation strategy is used, the standard errors of estimates. This question seemed simple, but i cannot find the answer in books. Iveware can be used under windows, linux, and mac, and with software packages like sas, spss, stata, and r, or as a standalone tool. Stata press, a division of statacorp llc, publishes books, manuals, and journals about stata and general statistics topics for professional researchers of all disciplines. Uk, and editor of the stata press book metaanalysis in stata. Both methods were essentially unbiased across the repeated samples.
This entry presents a general introduction to multiple imputation and. I got 3 imputed data sets which i do not know how to combine them and come up with one single set. The default in sas proc mi and stata mi command is 100 iterations between data sets. Feb 26, 2018 note that the number of postestimation commands after mi estimation is quite restricted compared to the vast array that is usually offered by stata. Overall, this book does an excellent job of bringing one from no knowledge of multiple imputation to a working knowledge of multiple imputation. Mrc clinical trials unit, london, and coauthor of the stata press book. This example is adapted from pages 114 of the stata 12 multiple imputation manual which i highly recommend reading and also quotes directly from the stata 12 online help. Multiple imputation before or after creating variables. Mi is attractive because it is both practical and widely applicable. Account for missing data in your sample using multiple imputation. However, one of the big uncertainties about the practice of multiple imputation is how many imputed data sets are needed to get good results. Multiple imputation can be used in cases where the data is missing completely at random, missing at random, and even when the data is missing not at random.
Multiple imputation and its application, by james r. Multiple imputation and its application stata bookstore. Missing data are a common occurrence in real datasets. I imputed data because i miss a fair part of my dichotomous outcome. Ive been reading posts here and there that says that i have to. Stata module to impute missing values using the hotdeck method, statistical software components s366901, boston college department of economics, revised 02 sep 2007. Furthermore, detailed guidance of implementation in r using the authors package mice is included throughout the book. Multiple imputation in mplus employee data data set containing scores from 480 employees on eight workrelated variables variables. This book focuses on a particular statistical method for analysing and drawing inferences from incomplete data, called multiple imputation mi. Choose from univariate and multivariate methods to impute missing values in continuous, censored, truncated, binary, ordinal, categorical, and count variables. Multiple imputation works well when missing data are mar eekhout et al. In longitudinal studies, special problems relate to attrition and death during followup. Multiple imputation of missing data using stata data and statistical.
Learn about statas multiple imputation features, including imputation methods, data management, estimation and inference, the mi control panel, and other. Many laboratory variables or study endpoints could be measured repeatedly over time. Mar 05, 2015 imputation by predictive mean matching. Most multiple imputation methods assume multivariate normality, so a common question is how to impute missing values from categorical variables. It would seem wise to try different imputation approaches and see if. This series is intended to be a practical guide to the technique and its implementation in stata, based on the questions sscc members are asking the ssccs statistical. If you have stata 11 or higher the entire manual is available as a pdf file. Missing data and multiple imputation columbia university. A practical guide to analysing partially observed data. Age, gender, job tenure, iq, psychological wellbeing, job satisfaction, job performance, and turnover intentions 33% of the cases have missing wellbeing scores, and 33% have missing satisfaction scores. Missing data takes many forms and can be attributed to many causes.
Multiple imputation in stata, part 1 website overview. Multiple imputation for missing data statistics solutions. In an example of count data with missing values, pahel et al. This is because many statistics that are required for postestimation are not easily defined in a multiple imputation context. You can learn more about multiple imputation in my book missing data or in my twoday course of the same name. While using stata 14 last year, i became aware that the sem command didnt natively support multiple imputation.
Missing dataimputation discussion what do i do after i. Stata s mi command provides a full suite of multipleimputation methods for the analysis of incomplete data, data for which some values are missing. Do i just run the sem models with different groups based on the imputation variable. Multiple imputation of categorical variables the analysis. Imputation statistics jump to navigation jump to search in statistics, imputation is the process of replacing missing data with substituted values. Multiple imputation for time series data with amelia package. Multiple imputation mi is a statistical technique for dealing with missing data. We will learn about multiple imputation, the \gold standard method for dealing with missing data. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the mice package as developed by the author.
Multiple imputation is essentially an iterative form of stochastic imputation. Stata press 4905 lakeway drive college station, tx 77845, usa 979. Multiple imputation and model selection cross validated. Multiple imputation of missing values the stata journal. Using multiple imputation to deal with missing data and attrition in longitudinal studies with repeated measures of patientreported outcomes.
Multiple imputation is fairly straightforward when you have an a priori linear model that you want to estimate. Actually, with the help of stata the practical difficulties in most cases are minor. Further discussion and an example of deterministic imputation can be found in craig enders book applied missing data analysis 2010. Both multiple imputations and the bootstrap are techniques for deriving confidence bands. Multipleimputation reference manual, stata release 16.
Over the last decade, multiple imputation has rapidly become one of the most widelyused methods for handling missing data. This book focuses on a particular statistical method for analyzing and drawing inferences from incomplete data called multiple imputation mi. Stata has a suite of multiple imputation mi commands to help users not only impute their data but also explore the patterns of missingness present in the data. Missing dataimputation discussion what do i do after i get. Books about statistics, including the latest additions to the bookstore, along with a subject index and search utility. However, the primary method of multiple imputation is multiple imputation by chained equations mice. Multiple imputation and its application is aimed at quantitative researchers and students in the medical and social sciences with the aim of clarifying the issues raised by the analysis of incomplete data data, outlining the rationale for mi and describing how to consider and.
Using multiple imputation to deal with missing data and. Hi everyone, im new to spss and somehow managed to run multiple imputation on my data set. We describe a methodological approach for the use of multiple imputation mi to meet these challenges. We used multiple imputation with stata s ice command to handle missing data on all missing variables, following the what works clearinghouse version 4. Multiple imputation has solved this problem by incorporating the uncertainty inherent in imputation. The manuscript by royston and white 2011 describes ice which is the stata module of the approach using the fully automatic pooling to produce multiple imputation. Actually, it is not even designed to obtain correct point estimates although it can do this. Multiple imputation mi without considering time trend of a variable may cause it to be unreliable. However, things seem to be a bit trickier when you actually want to do some model selection e. Paul allison, one of my favorite authors of statistical information for researchers, did a study that showed that the most common method actually gives worse results that listwise deletion. Missing dataimputation discussion what do i do after i get my multiply imputed data.